From the sound of your question, im guessing you havent shot pistols much. If thats the case, you should definitely find a range that rents out guns or hang around a range where you could shoot someones gun. Pistol shooting is a lot harder, but youll soon find that some are much easier to shoot than others.
The main choices that come to my mind are Sig, CZ, or Ruger LCP. Glocks arent bad, but id much rather have a DA/SA pistol with a chambered round. A DA isnt just going to discharge by a simple slip of the finger, but the safe action style of pistol might. If you consider in-the-pants carry, i wouldnt recommend a 1911. Excellent design, but not the best choice to have a c0cked and locked gun pointed at the inside of your leg. 1911s are also difficult to learn how to shoot with. CZ and Sig are known to have some of the finest pistols around, with models covering almost all sizes and calibers. Youll want the biggest caliber you can comfortably shoot, plus a gun that is comfortable to carry. If its uncomfortable, you might be tempted to leave it home, which obviously defeats the whole purpose. This is where the LCP comes into play, it is so small there is no way for it to be a problem. Just slide it in a mikes #1 and right into your pocket, you wont even notice it there. Not the most fun gun to shoot, or the easiest, but its small and gets the job done. Check out a few of these: CZ 75,CZ 82,CZ 83,CZ 97, and Sig P220.
The way this world is going, youd be dumb not to carry. People get robbed and killed everyday in broad daylight, people just do whatever they want. You have to be ready to protect your life, and possibly the lives of others.
* and i feel like those that open carry would be shot before anything even started.